President Trump is giving Senate GOP leaders a major headache with his decision to endorse Rep. Julia Letlow’s (R-La.) Senate campaign over Sen. Bill Cassidy’s (R-La.), tossing fresh uncertainty over key parts of their agenda and upending the race in a red state.

Republican Michele Tafoya, a former sideline reporter for the National Football League, is launching her campaign for Senate on Wednesday with a message squarely focused on what she calls a “crisis of leadership” in Minnesota.