Inter Miami returns to MLS action on Saturday, as they take on Florida rivals Orlando City SC in the second of their two MLS regular-season matches in 2025.

Orlando City and Inter Miami don't like each other much, and that usually results in goals being scored, as our MLS expert Jason Ence explains.

Orlando City and Inter Miami meet in the Florida Derby without Lionel Messi, who is sidelined due to injury, but with both clubs battling for position in the Eastern Conference and coming off strong Leagues Cup performances.

It won’t be an easy task for the Herons, though, despite their good form. Orlando sits sixth in the Eastern Conference on 41 points, only one point behind Miami in fifth with 42, and both teams are also having to balance Leagues Cup knockout stages with MLS commitments.

Inter Miami will be without Lionel Messi as they jump back into MLS competition on Sunday night against host and in-state rival Orlando City. Herons coach Javier Mascherano confirmed on Saturday that Messi will not travel for the game due to a "minor" muscle injury in his right leg.