A 12-year study reveals how disrupted sleep may predict Huntington’s disease onset, could link to changes in thinking and ...

New research maps Huntington’s disease progression like a symphony unraveling. The brain first overcommunicates, then loses sync, and finally falls silent, each stage driven by different biological ...

The Huntington’s disease mutation worsens over time like a dangerous snowball. By harnessing the power of the gene editing tool CRISPR, scientists may have found a way to interrupt the HD mutation and ...

This is a bit like a detective catching a villain earlier in a mystery, before they cause more havoc. The HDDMS gives doctors and researchers a sharper magnifying glass to track the disease’s subtle ...

Pridopidine (previously called huntexil) is an experimental oral drug being developed primarily for Huntington’s disease (HD), and now also for ALS. It was originally thought to act by influencing ...

Researchers have detected early changes in brain scans and biomarkers in young people with the Huntington’s disease gene, 20 years before symptoms are predicted to appear. These findings could help ...

Roche gave an update this week about GENERATION HD2, testing the HTT-lowering drug tominersen in people with HD. The trial is continuing, but only the higher dose will move forward. What does this ...

The HDBuzz editorial team had a virtual sit-down with HDBuzz founder, editor emeritus, Huntington’s disease (HD) researcher, and neurologist Professor Ed Wild. We laughed, we cried… actually we just ...

Tracking disease progression – time for an update Until now, people with Huntington’s disease have been categorized primarily based on their clinical symptoms. Physicians watch a patient walk, perform ...

As we wave goodbye to 2024, the HDBuzz team reflects on a year marked by significant progress, challenges, and hope. From breakthroughs at the lab bench, advancements in drug development, and both ...

If a drug successfully moves through all phases of the clinical trial process, the company behind the drug will then apply to the regulators for approval which would allow them to market and sell ...

Catch up on all of the latest updates from day 1 of the 2021 CHDI Huntington’s disease therapeutics conference #HDTC2021 including presentations from Wave, Roche and Triplet.