Setmelanotide cut BMI 16.5% in a trial for acquired hypothalamic obesity, easing hyperphagia, though adverse events require close monitoring. Setmelanotide produced a mean body mass index (BMI) ...

Obesity converts adipose tissue into an immuno-endocrine driver that promotes Th17 polarization and keratinocyte proliferation via adipokine dysregulation and chronic low-grade inflammation.

In 'The Burden of Alzheimer's Disease Agitation: Impact on Patients, Caregivers, and Quality of Life,' the expert neurologists examined the following critical questions: What is the impact that ...

A large UK cohort study found atopic dermatitis raises the risk of shingles by 28%, with the steepest risk in severe disease ...

The Women’s Health Initiative, launched in 1991 across 40 centers with >161,000 participants, materially influenced practice ...

The FDA approved Moderna’s Biologics License Application (BLA) for its mRNA-based flu vaccine, mRNA-1010 (mFlusiva; Moderna), ...

Nationwide difference-in-differences analysis (IPTW-adjusted) compared 180-day preadmission vs 180-day postdischarge HEDIS high-risk medication dispensing in TM vs MA hospitalization episodes.

Lp(a) is largely immutable across the lifespan, enabling a single adult measurement to identify inherited risk and trigger cascade screening given co-dominant inheritance patterns. Recurrent ASCVD ...

Katherine Wilemon, Family Heart Foundation, described the biggest unmet need when it comes to public awareness of Lp(a) and ...

Disease-modifying antirheumatic drug (DMARD) and tumor necrosis factor (TNF) cycling is a real and well-documented problem in ...

Accelerated approval positions RP1 plus nivolumab for advanced melanoma after progression on prior anti–PD-1 therapy, following two CRLs and a 10–3 advisory committee recommendation. In IGNYTE (n=140) ...

Anosheh Afghahi, MD, discusses biomarker testing, trial matching technology, and community-academic partnerships to improve ...