Prior to receiving CAR T-cell therapy, patients undergo lymphodepletion chemotherapy, explained Kerry Rogers, MD, The James.

A quasi-experimental difference-in-differences analysis of Virginia claims quantified NSAID dispensing in higher-risk cardiorenal populations across 2019–2021 and estimated pandemic-associated ...

Disease-modifying antirheumatic drug (DMARD) and tumor necrosis factor (TNF) cycling is a real and well-documented problem in ...

The FDA approved Moderna’s Biologics License Application (BLA) for its mRNA-based flu vaccine, mRNA-1010 (mFlusiva; Moderna), ...

Katherine Wilemon, Family Heart Foundation, described the biggest unmet need when it comes to public awareness of Lp(a) and ...

Noureddin framed the emergence of dual GLP-1/glucagon receptor agonism as a significant development, placing it alongside artificial intelligence as a transformative force in medicine, noting that ...

Accelerated approval positions RP1 plus nivolumab for advanced melanoma after progression on prior anti–PD-1 therapy, following two CRLs and a 10–3 advisory committee recommendation. In IGNYTE (n=140) ...

Eligibility definitions differ across reports, particularly whether prior failure on highest approved antiobesity dose is required versus documenting discussion of all standard treatments. A one-off ...

Anosheh Afghahi, MD, discusses biomarker testing, trial matching technology, and community-academic partnerships to improve ...

Six peptides received narrow advisory support for potential 503A Bulks List inclusion, an atypical outcome given FDA staff recommendations against all seven under review. Legal compounding remains ...

Prior authorization, coverage limits, and affordability screening increasingly determine when CAR T or bispecifics are ...

Young adults with sarcoma face challenges that extend well beyond treatment, and closing gaps in research funding and specialty care could improve outcomes for this population and beyond, according to ...