Route 66 has never met an oversized roadside novelty it didn’t like. Add a giant block of cheese to the historic highway.

SAINT DAVID, AZ (AZFamily) — An alleged intruder was shot and killed by a homeowner in southern Arizona early Sunday morning. Authorities were called to reports of a burglary in progress in a ...

Flash flooding destroyed nearly all footbridges over Bright Angel Creek, cutting off hiker access. Crews are assessing damage ...

A social media influencer known for posting viral videos of pranks has pleaded guilty to criminal impersonation in Arizona.

PHOENIX (AZFamily) — A man is dead after police say he ran a stop sign and collided with another vehicle in north Phoenix ...

A truck carrying mac and cheese overturned, spilling the powdered cheese mix onto the road. Police said the driver was taken to the hospital with non-life-threatening injuries.

We are tracking an extreme cooldown and storms headed to the Valley tonight. Paul Horton has your First Alert forecast.

Researchers involved in the study hope the molecular map can eventually lead to more targeted therapies for autism. Experts and advocates have applauded the new study, saying it may open the door for ...

Two law enforcement officers were assaulted, and deputies used pepper spray on a group to break up a fight at a high school ...

Nineteen Valley restaurants were named in the first-ever Michelin Guide Southwest, which highlights premier dining ...

So far this summer, the Valley has seen 40 days above 110 degrees, including a high of 113 degrees on Saturday.

PHOENIX (AZFamily) — One person is dead after a crash in central Phoenix on Saturday. Officers were called to the scene, near 35th and Glendale avenues, and found that three cars were involved in the ...