The 24th-ranked Louisville Cardinals look to rebound from an opening game loss when they take on the Villanova Wildcats in ...

One of Casale's top Week 2 college football picks: He is going Over 23.5 on the team total for Ohio State as the Buckeyes ...

The veteran southpaw brings a 4-0 career record and 1.40 ERA against Colorado into Friday night's matchup, while rookie right-hander Mason Adams takes the mound for the struggling visitors.

Sitting five games back in the wild-card race with 15 to play, Seattle opens a critical nine-game road trip as George Kirby battles Jeffrey Springs in a mound rematch.

Tampa Bay can become the first major league team to secure a postseason spot Friday as Drew Rasmussen takes the mound against Houston opener Miguel Ullola.

Carlos Rodon takes the mound as the AL wild-card leaders look to gain ground in the division race against a surging crosstown rival seeking a fifth consecutive victory.

DraftKings offers $200 in bonus bets after your first $5 wager for 49ers vs. Rams betting in Australia on Thursday ...

Federal prosecutors in Brooklyn have opened a criminal investigation one week after the NBA punished the Clippers ...

San Francisco scored 24 unanswered points and held Matthew Stafford to 155 yards, while Mike Evans hauled in six catches in his debut before 100,021 Melbourne spectators.

Pittsburgh rides a four-game winning streak into Wrigley Field seeking to stay alive in the playoff hunt, while the hosts counter with Shota Imanaga in hopes of snapping their four-game skid.

Darian Mensah and Luke Nickel each threw three touchdown passes as the Hurricanes scored on 11 of their first 12 possessions in a rout so lopsided both teams agreed to shorten the fourth quarter.

The SportsLine Projection Model is calling for the Vikings to walk away with a 22-20 victory at home over Green Bay.