Transcatheter aortic valve implantation (TAVI) for severe, isolated, native aortic regurgitation has been challenging with use of transcatheter heart valves designed for aortic stenosis (off-label use ...

We show that, compared with surgeon predictions and existing risk-prediction tools, our machine-learning model can enhance ...

Adolescents and young adults with diverse sexual and gender identities bear a disproportionate burden of health adversities.1 ...

Like many countries in recent years, Kenya has been facing its first mpox epidemic. Clotilde Bigot reports from Mombasa.

Immunotherapy—could that be an option for me, doctor?” is a question frequently asked by patients with colorectal cancer. The ...

Undiagnosed and uncontrolled hypertension remains one of the most important preventable causes of heart attack, stroke, chronic kidney disease, and dementia. In 2024, an estimated 1·4 billion people ...

Emotional distress among adolescents in most participating countries was higher in 2022 than in 2018, with disproportionate ...

With drastic reductions in health aid threatening essential services and millions of lives, WHO issues new guidance for countries to safeguard health budgets, limit out-of-pocket payments, and ...

The prevalence of overweight and obesity has reached pandemic proportions, affecting more than 1 billion people worldwide; it ...

Childhood hypertension affects a substantial and growing proportion of the global paediatric population, with prevalence varying considerably by diagnostic approach. These findings underscore the need ...

Acute kidney injury (AKI) is among the most common organ failures observed in the hospital and can irrevocably alter the ...

Sudan's ongoing nationwide conflict has triggered one of the world's worst humanitarian crises, displacing 13·9 million people,1 including more than 4 million individuals who have fled across borders.