One molecule, sulfolithocholylglycine, linked both to higher PFAS burdens and to later diabetes, surviving stringent statistical correction. Bile acid conjugates like this one help regulate lipid and glucose homeostasis, supporting the idea of a mechanistic bridge.

A new discovery could change how type 1 diabetes is diagnosed and managed in individuals of African descent, researchers say. In type 1 diabetes, the insulin-producing beta cells in the pancreas stop working in childhood or young adulthood.