The Eagles opened as 1-point road favorites in Kansas City in Week 2 at BetMGM with a total of 45.5. It would mark only the third time in Mahomes' career that he played as a home underdog in the regular season, and the first instance since the Chiefs were 1-point home underdogs in Week 9 of the 2023 season against the Miami Dolphins.

Travis Kelce had an eventful day in Brazil, where the Kansas City Chiefs faced the Los Angeles Chargers on Friday to kick off their 2025 NFL season.