SP+, ESPN metrics predict final score, provide point spread + win probability numbers for Friday night college football showdown between Louisville and James Madison

One of the best teams in the Group of 5 will be in the spotlight on Friday night. Not only is James Madison the clear favorite to win the Sun Belt Conference, but it also boasts one of the shortest prices to make the College Football Playoff of any team in the Group of 5.

Learn which TV channel or how to live stream the Louisville Cardinals vs. James Madison Dukes game, Friday, Sept. 5.

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WDRB has all your Louisville-area high school football coverage for Week 3, from scores and exceptional players to stunning highlights. Below are the final scores from around Kentucky and southern Indiana. Scroll down later to vote for the WDRB Sports Player of the Week.

Friday night college football kicks off with the Louisville Cardinals taking on the James Madison Dukes in this Week 2 college football showdown.

SportsLine's computer model simulated James Madison Dukes vs. Louisville Cardinals 10,000 times and released its college football best bets for Week 2

Louisville stays home to play James Madison in Week 2 of the 2025 college football season. Here's how to watch the game.