Week 1 of the 2025 NFL season saw many fantasy staples—like Josh Allen, Derrick Henry, Christian McCaffrey and Puka Nacua rack up those points. It also saw a few surprises, both good and bad.

Prior to making any waiver wire moves for Week 2, take a look at our running back suggestions below. See the list below for potential fantasy football targets you might be able to grab off of the waiver wire this week. Check out the full NFL schedule on FOX Sports!

We finally got a week of real, live NFL games, and, in true NFL fashion, we got some craziness as well, like the Bills pulling off a miraculous comeback on Sunday Night Football against the Ravens, Daniel Jones being the first quarterback this century to lead a team to points on all of their offensive drives,