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Expert picks for San Francisco-Seattle in Week 1

49ers vs. Seahawks: Expert picks for San Francisco-Seattle in Week 1
The San Francisco 49ers will take on the Seattle Seahawks on Sunday at Lumen Field. Here's who experts are taking in this NFC West matchup.
San Francisco 49ers at Seattle Seahawks: Predictions, picks and odds for NFL Week 1 game
USA Today's NFL experts make their picks for a Week 1 showdown between the Seattle Seahawks and San Francisco 49ers
When do the Seattle Seahawks play San Francisco 49ers? Time, TV channel, streaming
The Seattle Seahawks will host the San Francisco 49ers on Sept. 7 at Lumen Field in the opening game of the NFL regular season. This is Seattle head coach Mike Macdonald's second season leading the Seahawks. The former Ravens defensive coordinator was hired as the Seahawks' head coach in January 2024.
Seahawks vs. 49ers odds, prediction, bets: Proven model reveals free 2025 NFL Week 1 picks for Sunday
The SportsLine projection model reveals its picks for the NFL Week 1 game between the San Francisco 49ers and the Seattle Seahawks
49ers vs. Seahawks 2025 Prediction, Odds, Picks - Sep 7
Preview the Week 1 matchup between the San Francisco 49ers and Seattle Seahawks with predictions, odds, over/under, spread, betting lines and more.
49ers vs. Seahawks Final Score Prediction for NFL Week 1 (San Francisco’s Balance Gives Edge in Seattle)
San Francisco kicks off 2025 trying to erase the memory of an injury-riddled 2024 campaign, but despite those woes, their underlying efficiency metrics still ra
49ers vs. Seahawks: San Francisco elevates two players for Week 1 battle with Seattle
The San Francisco 49ers could use some reinforcements for their game against the Seattle Seahawks, so they're bringing up two practice squad players.
49ers elevate 2 players for Seahawks game, but there’s a catch
San Francisco elevated wide receiver Russell Gage and linebacker Curtis Robinson from the practice squad for the upcoming NFC West showdown, per NFL Network's Mike Garafolo. Surprisingly, the Niners did not add an RB to their active roster. Whatever concerns there are regarding McCaffrey appear to be minimal.
49ers vs. Seahawks: 4 things to know heading into the Week 1 matchup
The San Francisco 49ers and Seattle Seahawks will meet on Sunday for a Week 1 battle. Here's what fans should know heading into the game.
49ers promote 2, but don’t elevate a running back for Week 1 vs. the Seahawks
Head coach Kyle Shanahan had said it was likely that Gage would be up to give the 49ers an extra receiver on gameday. San Francisco initially had Gage on the 53-man roster, but released him and signed him to the practice squad to promote recently-signed Marques Valdez-Scantling to the active roster.
Seahawks elevates former starter for 49ers showdown
The Seahawks are adding a familiar face to their active roster ahead of the season opener against the rival 49ers.

49ers at Seahawks odds

The San Francisco 49ers and the Seattle Seahawks open their seasons Sunday. Kickoff from Lumen Field is scheduled for 4:05 ...

How to Watch Seahawks vs. 49ers: Time, TV Channel and Live Stream – 2025 Week 1

Learn which TV channel or how to live stream the NFL Week 1 Seattle Seahawks and San Francisco 49ers game, Sunday, Sept. 7.

Where to watch 49ers vs. Seahawks: TV channel, kickoff time, odds, prediction

A division as difficult as the NFC West has become cannot be won in Week 1. But winning or losing the first divisional ...