Understanding Pepto-Bismol Pepto-Bismol contains the ingredient bismuth subsalicylate. It is an antidiarrheal medication taken to manage nausea, upset stomach, diarrhea, and heartburn.

The active ingredient in Pepto Bismol, bismuth subsalicylate, may not help with prevention of diarrhea while traveling, a study found.

For nearly a century, Pepto-Bismol has stood for relief of stomach troubles. To celebrate its 99th anniversary, the iconic brand is excited to introdu ...