Background In autumn 2024 the UK introduced a maternal vaccine against respiratory syncytial virus, with the aim of a ...

Background Paediatric research is critical for evidence-based clinical care and public health policy, yet children remain under-represented in UK biomedical research. Despite comprising 20% of the ...

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While the methodological principle of ‘blinding’ for minimising bias in randomised controlled trials (RCT) is widely debated and accepted, rarely is this depth of thinking applied to its correct ...

This review covers the basic principles of systematic reviews and meta-analyses. The problems associated with traditional narrative reviews are discussed, as is the role of systematic reviews in ...

Objective Core outcome sets are the baseline for what should be measured in clinical research and, thus, should serve as a guide for what should be collected and reported. The Consensus Group on ...

Aim Gender dysphoria (GD) refers to the psychological distress associated with the incongruence between one’s sex and one’s gender identity. To manage GD, individuals may delay the development of ...

Correspondence to Dr Ishaq Abu-Arafeh, Department of Paediatrics, Forth Valley Royal Hospital, Larbert, Stirlingshire FK5 4WR, UK; iabu-arafeh{at}nhs.net Objective To study the clinical and ...

Correspondence to Dr Mary E Ramsay, Department of Immunisation, Hepatitis and Blood Safety, Public Health England, 61 Colindale Avenue, London NW9 5EQ, UK; Mary.ramsay{at}phe.gov.uk By 2010, the ...

Objective To describe infants with acute gastroenteritis symptoms in primary and secondary care who have the Rotarix vaccine-derived G1P[8] rotavirus strain identified in their stools. Design This is ...

a Department of Child Health, University of Newcastle upon Tyne, Newcastle upon Tyne NE8 1EB, UK, b Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK Dr C M Wright, Community Child Health Unit ...

4 School of Clinical Medical Sciences (Child Health), Sir James Spence Institute of Child Health, Royal Victoria Infirmary, Newcastle upon Tyne, UK 5 Division of Health in the Community, Warwick ...