Multiple long-term conditions (MLTC, previously referred to as multimorbidity) are defined as two or more chronic health ...

Paediatric sepsis remains a major cause of childhood mortality worldwide, despite substantial changes in its epidemiology, ...

Background Studies from low-income countries have suggested that diphtheria-tetanus-pertussis (DTP) vaccine provided after Bacille Calmette-Guerin (BCG) vaccination may have a negative effect on ...

Participants Babies with an NTD and pregnancy outcome of live birth, stillbirth (≥20 weeks’ gestation) or termination of pregnancy (any gestation), as recorded in the Scottish Linked Congenital ...

Aims: To estimate the annual incidence of hospitalisations due to severe complications of varicella, describe the complications and estimate annual mortality. Methods: Active surveillance throughout ...

Background The diagnostic value of tests used in assessing hypothalamic-pituitary-adrenal axis (HPA) in children remains controversial. Design A systematic review and meta-analysis with ...

Despite the existence of low-cost and effective interventions for childhood pneumonia and diarrhoea, these conditions remain two of the leading killers of young children. Based on feedback from health ...

Correspondence to Marije A Brouwer, Department of Pediatrics, University Medical Center Groningen, Groningen 9700 VB, Netherlands; m.a.brouwer{at}umcg.nl Objective Breaking bad news about ...

Objective When infants suffer from nasal congestion, xylometazoline spray or drops can be effective to facilitate breathing and drinking. However, case reports on side effects have resulted in ...

In 2025, a government-commissioned, independent, cross-sector report on the decline in UK clinical academia highlighted multiple challenges facing clinical researchers, both those medically qualified ...

Confidentiality is the cornerstone of effective adolescent healthcare. The trust that sensitive information will be protected enables young people to disclose critical health concerns related to ...

Since the onset of the COVID-19 pandemic, paediatricians and child mental health practitioners have noticed an increase in tic symptoms in some children and adolescents already diagnosed with tic ...