Multiple long-term conditions (MLTC, previously referred to as multimorbidity) are defined as two or more chronic health ...

Paediatric sepsis remains a major cause of childhood mortality worldwide, despite substantial changes in its epidemiology, ...

Background Studies from low-income countries have suggested that diphtheria-tetanus-pertussis (DTP) vaccine provided after Bacille Calmette-Guerin (BCG) vaccination may have a negative effect on ...

Aims: To estimate the annual incidence of hospitalisations due to severe complications of varicella, describe the complications and estimate annual mortality. Methods: Active surveillance throughout ...

Participants Babies with an NTD and pregnancy outcome of live birth, stillbirth (≥20 weeks’ gestation) or termination of pregnancy (any gestation), as recorded in the Scottish Linked Congenital ...

Correspondence to Marije A Brouwer, Department of Pediatrics, University Medical Center Groningen, Groningen 9700 VB, Netherlands; m.a.brouwer{at}umcg.nl Objective Breaking bad news about ...

Background The diagnostic value of tests used in assessing hypothalamic-pituitary-adrenal axis (HPA) in children remains controversial. Design A systematic review and meta-analysis with ...

Dr Astrid E Lammers, Department of Paediatric Cardiology, Great Ormond Street Hospital for Children, Great Ormond Street, London WC1N 3JH, UK; astridlammers{at}gmx.de Objective: The 6-minute walk test ...

Correspondence to Dr Defne Saatci, Population Policy Practice, Institute of Child Health, London WC1N 1EH, UK; defne.saatci.16{at}ucl.ac.uk Objective To assess differences across educational outcomes ...

Introduction Fluid overload of 10% at 48 hrs (100 ml/kg additional fluid) is strongly associated with morbidity in critically ill children.1 Contributors include fluid resuscitation, acute kidney ...

Aims To assess whether auscultation findings at presentation with bronchiolitis vary with age or viral aetiology. Methods We conducted an opportunistic prospective cohort study of infants who ...

Objective Skeletal surveys play an important role in detecting occult injury in young children at risk from non-accidental ...