Objective To update the evidence on efficacy and safety of biological disease-modifying antirheumatic drugs (bDMARDs) in patients with axial spondyloarthritis (axSpA) to inform the 2022 update of the ...

The use of immunosuppressive medications in people with hepatitis B virus (HBV) infection is associated with an increased risk of HBV reactivation, which can lead to liver failure and death. Tumour ...

Background Unmet medical need continues to be significant in patients with systemic lupus erythematosus (SLE) despite the use of advanced therapies (AT) to control active disease. Fatigue, end-organ ...

The objective was to develop evidence-based recommendations for the management of antiphospholipid syndrome (APS) in adults. Based on evidence from a systematic literature review and expert opinion, ...

4 Leiden University Medical Center, Department of Orthopaedics, Leiden, Netherlands 5 Leiden University Medical Center, Department of Biomedical Data Sciences, Leiden, Netherlands Objectives The ...

5 Department of Rheumatology, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands 6 Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, The ...

Objectives The dynamics of monosodium urate (MSU) crystal changes across a range of serum urate concentrations in people with gout are unknown. This study aimed to systematically examine the ...

SpA: Innovative techniques in spondyloarthritis research – Is there light at the end of the tunnel for our patients?

‘Poly-refractory’ disease affects 2.7% of patients with rheumatoid arthritis (RA) who have failed different groups of biologic disease-modifying antirheumatic drugs (b-DMARDS) and targeted synthetic ...

Background Evidence suggests that timely and effective management can improve long-term outcomes in patients (pts) with psoriatic arthritis (PsA); however factors influencing treatment management ...

We read with interest the recent article by Singh and Cleveland on the hypersensitivity risk of allopurinol (ALP) and febuxostat (FBX) compared with colchicine.1 A common challenge when using ALP, ...

1 Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, Maastricht, The Netherlands 2 Department of Rheumatology, Maasland Hospital Sittard, The Netherlands 3 ...