BMJ

POS1153 PRELIMINARY EVALUATION OF THE SAFETY AND ANALGESIC EFFICACY OF THE TRPV1 AGONIST RTX-GRT7039 IN KNEE OSTEOARTHRITIS: A RANDOMISED, DOUBLE-BLIND ...

Background: RTX-GRT7039 (resiniferatoxin; RTX), is a potent and selective agonist of the transient receptor potential vanilloid 1 (TRPV1) being developed for treatment of pain related to knee ...
BMJ

Low disease activity (DAS28≤3.2) reduces the risk of first cardiovascular event in rheumatoid arthritis: a time-dependent Cox regression analysis in a large cohort study

Correspondence to Elke EA Arts, Department of Rheumatology, Radboud University Medical Centre, Geert Grooteplein 8, 6500 HB Nijmegen, The Netherlands; elkearts{at}gmail.com, elkearts{at}hotmail.com ...
BMJ

Prevalence, incidence and progression of hand osteoarthritis in the general population: the Framingham Osteoarthritis Study

3 Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, Massachusetts, USA 4 Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts, USA ...
BMJ

EULAR evidence-based recommendations for the diagnosis of knee osteoarthritis

15 Department of Radiology. Leiden University Medical Centre, Leiden, The Netherlands 16 Department of Rheumatology and Clinical Immunology, University Medical Centre Utrecht, Utrecht, The Netherlands ...
BMJ

Evaluation of WOMAC 20, 50, 70 response criteria in patients treated with hylan G-F 20 for knee osteoarthritis

2 Rheumatology and Clinical Epidemiology, Sunnybrook & Women’s Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada 3 Department of Clinical Epidemiology and Biostatistics, McMaster ...
BMJ

Physician global assessment in systemic lupus erythematosus: can we rely on its reliability?

We read with great interest the recent paper by Aranow et al 1 about the impact of laboratory results on scoring of the Physician Global Assessment (PGA) of disease activity in systemic lupus ...
BMJ

Is a 1-year course of methotrexate in patients with arthralgia at-risk for rheumatoid arthritis cost-effective? A cost-effectiveness analysis of the randomised, placebo ...

Objectives Rheumatoid arthritis (RA) has a considerable disease burden with life-long physical limitations, reduced work productivity and high societal costs. Trials on arthralgia at-risk for RA are ...
BMJ

Risk of systemic lupus erythematosus in patients with idiopathic thrombocytopenic purpura: population-based cohort study

We read with great interest the article by Zhu et al .1 It was based on a national study regarding the association between idiopathic thrombocytopenic purpura (ITP) and the subsequent development of ...
BMJ

Relationship between serum urate and changes in dual-energy CT monosodium urate crystal volume over 1 year in people with gout: an individual participant data analysis

Objectives The dynamics of monosodium urate (MSU) crystal changes across a range of serum urate concentrations in people with gout are unknown. This study aimed to systematically examine the ...
BMJ

LB0002 RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTIPLE-DOSE, PHASE 2B STUDY TO DEMONSTRATE THE SAFETY AND EFFICACY OF TILDRAKIZUMAB, A HIGH ...

5 Sun Pharmaceutical Industries, Inc., Princeton, United States of America 6 Cincinnati Rheumatic Disease Study Group, Inc., Cincinnati, United States of America 7 University of Cincinnati College of ...
BMJ

Correspondence on ‘Efficacy of a tight-control and treat-to-target strategy in axial spondyloarthritis: results of the open-label, pragmatic, cluster-randomised TICOSPA trial’

Correspondence to Xiaoqing Peng, Department of Obstetrics and Gynaecology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230032, China; pengxiaoqing{at}ahmu.edu.cn We read with ...
BMJ

The squeeze test of MCP joints: a scarcity of scientific data, especially from primary care

1 Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands 2 Department of Rheumatology, Erasmus Medical Center, Rotterdam, The Netherlands Correspondence to A H M van der ...