BMJ

Quadriceps weakness in knee osteoarthritis: the effect on pain and disability

a Rheumatology Unit, City Hospital, Nottingham NG5 1PB, b Department of Public Health Medicine and Epidemiology, Queens Medical Centre, Nottingham Dr O’Reilly. OBJECTIVES (1) To determine the ...
BMJ

ASAS consensus definition of early axial spondyloarthritis

Objectives To develop a consensual definition for the term ‘early axial spondyloarthritis—axSpA’—and ‘early peripheral spondyloarthritis—pSpA’. Methods The ASAS (Assessment of SpondyloArthritis ...
BMJ

Risk of systemic lupus erythematosus in patients with idiopathic thrombocytopenic purpura: a population-based cohort study

Correspondence to Dr James Cheng-Chung Wei, Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan; jccwei{at}gmail.com Background Idiopathic thrombocytopenic purpura (ITP) may play a ...
BMJ

Ankylosing Spondylitis Disease Activity Score (ASDAS): defining cut-off values for disease activity states and improvement scores

2 Rheumatology Department, Leiden University Medical Center, Leiden, The Netherlands 3 Rheumatology Department, Maastricht University Medical Center, Maastricht, The Netherlands Background The ...
BMJ

Prevalence, incidence and progression of hand osteoarthritis in the general population: the Framingham Osteoarthritis Study

3 Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, Massachusetts, USA 4 Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts, USA ...
BMJ

Activated human B cells induce inflammatory fibroblasts with cartilage-destructive properties and become functionally suppressed in return

Background Cross-talk between synovial fibroblasts (SF) and immune cells is suggested to play a crucial role in inflammation and chronification of rheumatoid arthritis (RA). The contribution of B ...
BMJ

Low disease activity (DAS28≤3.2) reduces the risk of first cardiovascular event in rheumatoid arthritis: a time-dependent Cox regression analysis in a large cohort study

Correspondence to Elke EA Arts, Department of Rheumatology, Radboud University Medical Centre, Geert Grooteplein 8, 6500 HB Nijmegen, The Netherlands; elkearts{at}gmail.com, elkearts{at}hotmail.com ...
BMJ

Endothelial-to-mesenchymal transition contributes to endothelial dysfunction and dermal fibrosis in systemic sclerosis

Correspondence to Dr Mirko Manetti, Department of Experimental and Clinical Medicine, Section of Anatomy and Histology, University of Florence, Largo Brambilla 3, Florence 50134, Italy; ...
BMJ

What is the evidence for the presence of a therapeutic window of opportunity in rheumatoid arthritis? A systematic literature review

1 Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands 2 Walaeus Library, Leiden University Medical Center, Leiden, The Netherlands 3 Department of Clinical ...
BMJ

POS1153 PRELIMINARY EVALUATION OF THE SAFETY AND ANALGESIC EFFICACY OF THE TRPV1 AGONIST RTX-GRT7039 IN KNEE OSTEOARTHRITIS: A RANDOMISED, DOUBLE-BLIND ...

Background: RTX-GRT7039 (resiniferatoxin; RTX), is a potent and selective agonist of the transient receptor potential vanilloid 1 (TRPV1) being developed for treatment of pain related to knee ...
BMJ

Rheumatoid arthritis increases the risk of deep vein thrombosis and pulmonary thromboembolism: a nationwide cohort study

Correspondence to Dr Chia-Hung Kao, Graduate Institute of Clinical Medicine Science, College of Medicine, China Medical University, No. 2, Yuh-Der Road, Taichung 40447, Taiwan; d10040{at}mail.cmuh.org ...
BMJ

Tacrolimus versus mycophenolate mofetil for induction therapy of lupus nephritis: a randomised controlled trial and long-term follow-up

Correspondence to Dr Chi Chiu Mok, Department of Medicine, Tuen Mun Hospital, Hong Kong; ccmok2005{at}yahoo.com Objective To compare the efficacy of tacrolimus (TAC) and mycophenolate mofetil (MMF) ...