UC San Diego researchers have received an $11.3 million contract to develop "smart" red blood cells to give soldiers an ...

Jose De Jesus Anguiano offered money, marijuana and alcohol to four minors between the ages of 13 and 17 as part of attempts to coerce them into engaging in sexual acts with him, authorities said.

A pedestrian lost his life over the weekend to a late-night hit-and-run in Escondido, authorities reported Monday.

Tuesday marks the first day that San Diegans can hail a public ride in an autonomous Waymo vehicle. Waymo is expanding its ...

A homicide investigation is underway after a victim was found dead in Clairemont, according to the San Diego Police ...

The two men running in Escondido's mayoral race will square off Tuesday in a debate centered on one of the region's most ...

Manny Machado had four hits, Michael King struck out six in six innings and the San Diego Padres defeated the Cincinnati Reds ...

The Monarch School has been temporarily closed, and students have been relocated over concerns about possible mold on campus.

SD County Board of Supervisors Paloma Aguirre & Terra Lawson-Remer are hoping to forward a plan approved to allow the County ...

Hugo Parra and Ariel Alonso Beltran were arrested in November after officers used an ALPR hit on a car's make and model — not ...

Northbound lanes of I-5 and five outside lanes of northbound I-805 will be closed overnight beginning Monday night for ...

Thieves made off with tens of thousands of cans of Pabst beer in two separate heists from a Southern California warehouse on ...