Key points A 39-year-old woman with a known history of antiphospholipid syndrome (APS) presented to the emergency department ...

Sentinel injuries are minor, unexplained injuries in pre-cruising infants that are often the first indication of physical abuse, which may precede more serious harm.[1][1],[2][2] In one study, more ...

Key points In November 2025, Canada lost its measles elimination status, which it had held since 1998.[1][1] From October 2024 to November 2025, more than 5000 measles cases associated with a large ...

A 31-year-old pregnant woman (35 weeks’ gestation; gravida 2, para 1) presented to the emergency department with a 2-day history of progressively painful, bright red facial erythema ([Figure 1][1]).

The day was blistering and the road shimmered with heat. I was seven years old when I asked to cross the street alone for ice cream. It was meant to be a small rite of passage, a step toward freedom.

Infections of cardiovascular implantable electronic devices (CIEDs) occur at a rate of about 1% in the first year 1, 2 One year mortality after infection is 15–30% 3 In 2021, 120 000 people in Canada ...

Intranasal corticosteroids are safe, but local adverse effects are common One in 10 patients have local adverse effects, including burning or stinging, dryness and epistaxis. 2 Systemic adverse ...

Key points An estimated 8.7 million premature deaths occur globally each year from air pollution attributable to fossil fuel ...

Chronic noncancer pain includes any painful condition that persists for at least three months and is not associated with malignant disease. [1] [1] According to seven national surveys conducted ...

Kelly Ann Hutchinson, Sena Turkdogan and Lily H.P. Nguyen ...

A 2-year-old girl presented to the dermatology clinic with a 2-week history of a solitary perianal protrusion. Her parents said she had shown no signs of pain or pruritus. She had no history of ...

Key points A 69-year-old man presented to the emergency department with several months of progressive weakness, exertional dyspnea, and recurrent sinopulmonary infections. Over the preceding 6 months, ...