See related article at Key points In this issue of CMAJ , Geboe and colleagues present the results of a qualitative community-based participatory study of Inuit experiences of the ongoing epidemic of ...

Cognitive impairment occurs in 34% to 65% of people with MS,[1][1] with an elevated prevalence in those with disease of many years’ duration, heightened physical disability, and progressive illness ...

Key points A 69-year-old man presented to a dermatology clinic with a 1-day history of a painful erythematous rash. Four days ...

Blood pressure normally peaks three to six days postpartum in both normotensive women and those with previous hypertension. [1] [1], [2] [2] Pain, drugs (e.g., nonsteroidal anti-inflammatory drugs ...

In October 2018, recreational use of cannabis was legalized in Canada with the primary objectives of improving cannabis-related public health and safety, reducing youth access to cannabis, and ...

Background: Although brain and heart conditions share overlapping risk factors and commonly co-occur, current cardiac and neurologic clinical guidelines are typically produced within specialty silos.

Canada’s civilian health system would likely bear the clinical burden of large-scale casualty events involving Canadian or allied forces, yet the country lacks a national framework to coordinate ...

A 69-year-old man with hypertension and hyperlipidemia presented to the emergency department with exertional angina. Coronary artery catheterization demonstrated 80% stenosis in the left anterior ...

Key points Sickle cell disease (SCD) occurs when a DNA base pair substitution in the β-globin gene results in the formation of hemoglobin S, which polymerizes when deoxygenated, leading to deformation ...

Background: Physician work hours directly influence patient access to health care services and play a vital role in physician human resource planning. We sought to evaluate long-term trends in hours ...

What are the key steps of the exploration phase? The development of successful machine-learned solutions requires a deep understanding of the problem at hand, relevant outcomes, the data that are ...