Recommendation The Canadian Task Force on Preventive Health Care recommends against instrument-based depression screening using a questionnaire with cut-off score to distinguish “screen positive” and ...

A healthy 8-year-old boy presented to our dermatology clinic with a 4-week history of worsening movement limitation and pain due to skin retraction of the right axilla. There were no constitutional ...

A 34-year-old woman (gravida 3, para 2) at 16 weeks’ gestation was found to have platelets unable to be quantified because of clumping on routine prenatal blood work, with a visual estimate of 40 ...

In June 2026, 2 Canadian cities will host several FIFA World Cup soccer matches. Health care systems may have to play host too, as large numbers of visitors to these cities will increase pressure on ...

Key points The definition and criteria used for reporting stillbirths in Canada are idiosyncratic and dated, and directly responsible for the country’s artificially high and rising stillbirth rate ...

Intramuscular epinephrine rapidly reverses airway edema and shock.[1][1] Current evidence does not support use of antihistamines and corticosteroids to prevent progression of anaphylaxis or biphasic ...

Key points A 75-year-old woman presented to the emergency department with acute confusion and lethargy on the third day of ...

In patients who inject insulin, the most common cause of a soft-tissue abdominal mass is lipohypertrophy; however, insulin-derived amyloidosis should be included in the differential diagnosis for ...

Although tuberculosis (TB) disease is preventable and curable, it affects nearly 11 million people worldwide each year, more than 2000 of whom live in Canada. In Canada, TB overwhelmingly affects ...

The prevalence rises with age, reaching 5% to 7% among patients older than 70 years.[1][1] The differential diagnosis of an adrenal mass includes adenomas (both functional and nonfunctional), ...

Effect of insulin resistance on ticagrelor-versus clopidogrel-based dual antiplatelet therapy for secondary prevention of stroke in carriers of CYP2C19 loss-of-function mutations ...

Pain from vaccine injections is common, and concerns about pain contribute to vaccine hesitancy across the lifespan.1,2 Noncompliance with vaccination compromises the individual and community benefits ...