KEY POINTS Acute aortic syndrome (AAS) is a life-threatening emergency, accounting for 1/2000 presentations of acute chest or back pain to the emergency department. [1] [1] It is a clinical spectrum ...

An important flaw in the funding approach used by Canada’s public drug plans is highlighted by the findings of 2 articles related to the clinical value of direct oral anticoagulants (DOACs), published ...

We do a very poor job of health workforce planning in Canada, in large part because of inadequate health workforce data. Inadequate health workforce data have economic costs because poor data limit ...

Wernicke encephalopathy is a medical emergency with substantial morbidity and mortality A historical case series reported mortality in 17% of patients with acute Wernicke encephalopathy. 2 Of the ...

Since late 2023, new outbreaks have been reported in Bolivia, Brazil, Peru, and Cuba, including among travellers returning to Canada and the United States. [1] [1], [2] [2] Malaria, Zika, dengue, and ...

Background: Cancer surveillance data are essential to help understand where gaps exist and progress is being made in cancer control. We sought to summarize the expected impact of cancer in Canada in ...

Smoking marijuana can increase clearance of some drugs Smoked marijuana increases the clearance of theophylline 40%. 1 Similar findings would be expected for other drugs metabolized by CYP1A2, such as ...

Background: Fragility fractures are a major health concern for older adults and can result in disability, admission to hospital and long-term care, and reduced quality of life. This Canadian Task ...

Recreational use of nitrous oxide is a growing problem in many jurisdictions, including Canada. Although isolated, short-term use rarely leads to serious complications, chronic use can cause ...

Jacqueline M. McMillan, Elizabeth Aitken and Jayna M. Holroyd-Leduc The appropriate assessment and management of chronic insomnia is crucial. Insomnia affects quality of life and has been shown to be ...

A recent meta-analysis showed that, compared with the left-lateral going-to-sleep position, the supine going-to-sleep position was associated with stillbirth (adjusted odds ratio [OR] 2.63, 95% ...

Postinfectious cough affects 11%–25% of adults after a respiratory infection Postinfectious cough is defined as a subacute cough, with symptoms lasting between 3 and 8 weeks. 1 The preceding infection ...