Whether treatment with balanced crystalloid fluid leads to better outcomes than 0.9% saline in children treated for septic ...

Blood-pressure reduction is the only proven treatment to prevent stroke. Whether a single pill that combines three ...

Overactivation of the alternative complement pathway contributes to IgA nephropathy and glomerular inflammation. In the 9-month interim analysis of this phase 3 trial, iptacopan, a complement factor B ...

The Pediatric Research Equity Act was intended to promote the development and testing of prescription drugs for children. But ...

Post-thrombotic syndrome is common after deep-vein thrombosis and can cause severe symptoms involving the limbs that impair patients’ activity and quality of life. Endovascular therapy can ...

Despite the implementation of efficacious interventions for secondary prevention, patients with ischemic stroke or transient ischemic attack (TIA) remain at substantial residual risk for short- and ...

Utah recently rolled out a pilot program involving an AI system that autonomously renews certain prescriptions for people with chronic conditions. This program raises important clinical and legal i ...

A 16-year-old girl presented with 1 month of ankle pain and 11 days of fever. Radiographs showed an ill-defined, radiolucent distal tibial lesion; on MRI, the lesion was hypointense and surrounded by ...

Post-thrombotic syndrome is the most common chronic complication of deep-vein thrombosis (DVT), affecting 20 to 50% of patients with DVT and causing debilitating symptoms involving the limbs — ...

Explore this issue of The New England Journal of Medicine (Vol. 394 No. 5).

A 30-year-old man with aplastic anemia presented with fever, nonpruritic rash, and ankle and knee pain. Ten days before presentation, he had completed a course of horse antithymocyte globulin.