The Indian Health Service has limited options for recruiting physicians to its most understaffed sites. Partnerships with academic medical centers could help address long-standing physician shortages.

Progress against the U.S. HIV epidemic is stalling, owing in part to government attacks and fear. But clinicians, patients, and activists can learn from the epidemic’s early heroes and find ways ...

A 72-year-old man with hypertension, hyperlipidemia, and a stable ascending aortic aneurysm presented with sudden-onset, ...

Many patients with chronic obstructive pulmonary disease (COPD) have exacerbations despite receiving standard-of-care inhaled ...

Trichodysplasia spinulosa–associated polyomavirus was identified as a likely cause of neuroinvasive infection in a ...

A 3-year-old boy with chemotherapy-resistant metastatic hepatoblastoma had complete regression lasting at least 12 months after two infusions of glypican-3–specific CAR T cells coexpressing ...

A 65-year-old man was admitted to this hospital because of fever, intermittent abdominal pain, and rash. The fever began 5 weeks earlier, and palpable purpura developed 1 week before admission. A ...

Whether catheter-directed thrombolysis improves clinical outcomes in patients with intermediate-high–risk pulmonary embolism, ...

Approximately one half of patients undergoing transcatheter aortic-valve implantation (TAVI) have concomitant coronary artery ...

Pulmonary hypertension that is caused by left heart disease and is associated with heart failure may be driven by sympathetic ...

For more than 25 years, narcolepsy type 1 (formerly narcolepsy with cataplexy) has been known to be associated with a deficiency of orexin within cerebrospinal fluid (CSF) and reduced staining of ...

Stroke is a severe and common complication of atrial fibrillation. Anticoagulation with vitamin K antagonists or with direct oral anticoagulants (DOACs) prevents the majority of strokes in patients ...