A 28-year-old woman presented to the emergency department because of abdominal pain, nausea, vomiting, and dizziness. The body-mass index was 18, and the anion gap was elevated. A diagnosis was made.

A 55-year-old man with a smoking history of 10 pack-years presented with 2 years of an enlarging, painless lump below his right ear. A previously unnoticed smaller mass in the left parotid gland ...

A study noted a sharp increase in leucovorin prescriptions dispensed to children (≤17 years of age) after a plan was ...

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 13).

Core elements of the pay-for-performance approach have inherent shortcomings. Achieving meaningful quality improvement at scale may require rethinking this paradigm.

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 4).

To the Editor: The CORALreef Lipids trial, conducted by Navar et al. (Feb. 5 issue), 1 showed a marked reduction from baseline in the low-density lipoprotein (LDL) cholesterol level with the oral ...

How can we change a system, and a culture, in which suicide can look to physicians like an attractive escape from the relentless demands of medical practice?

As the health of his brother and running buddy rapidly declines and he faces his own health scares, a physician feels compelled — and grateful — to keep moving forward.

Increasing pandemic frequency and increasing economic inequality are creating a self-reinforcing cycle. What’s needed is therefore a new, inequality-informed approach to pandemic preparedness.

This editorial describes the science behind a study of mezigdomide, which augments the degradation of the proteins Ikaros and Aiolos, to treat multiple myeloma.