A man presented with a painless enlargement of the left testicle. Owing to concern about testicular cancer, an orchiectomy was performed. Histopathological examination showed granulomatous inflamma ...

A 71-year-old man presented to the emergency department with fever and left hand pain after eating raw seafood. Surgical wound cultures identified Vibrio vulnificus.

Medical schools have been moving away from lecture-based courses. Questions remain, however, regarding what content students must learn, how that learning is best done, and what else is required fo ...

The AHEAD model was intended to slow health care cost growth, improve population health, and advance health equity. But under the new administration, its focus has shifted from equity to efficiency.

A 91-year-old man was admitted to the hospital with weight loss, dyspnea, and eosinophilia. An anteroposterior chest radiograph obtained 2 months earlier showed bibasilar patchy opacities. A ...

A 91-year-old man with a history of bladder carcinoma and left total knee arthroplasty was evaluated because of left knee pain. A culture of synovial fluid showed no growth. A diagnosis was made.

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 19).

This Sounding Board announces a new FDA policy that the default requirement for FDA approvals will be one robust pivotal trial plus confirmatory evidence, rather than two trials.

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 20).

The most important attribute of patient-centered care is the active engagement of patients when fateful health care decisions must be made — when they arrive at a crossroads of medical options, where ...

Medical credit cards have emerged as a popular financing tool for patients seeking care they might otherwise be unable to afford. But these cards may ultimately increase financial burdens on patients.

A 7-year-old boy was brought to a hospital with a 3-month history of cognitive deterioration and seizures. He had contracted measles at 7 months of age while living in an area where the infection is ...