Tuberculosis remains a leading cause of death worldwide among persons with HIV. In this report, the effect of the PEPFAR ...

Data are needed on the effect of oxygen delivered through a high-flow nasal cannula, as compared with standard oxygen therapy, on intubation and mortality in patients with acute hypoxemic ...

States have responded to increasing health care consolidation by enhancing their review of mergers and acquisitions. But some states have carved out certain academic medical centers from such ...

Recent changes in U.S. vaccine policy are sowing confusion and threatening the health of children and the wider population.

Whole-blood transfusion has recently gained favor in the management of severe hemorrhage; however, data from large clinical trials evaluating its clinical effectiveness and safety are lacking. We ...

In patients with refractory systemic lupus erythematosus, in vivo generation of CD19 CAR T cells by means of lipid nanoparticles led to B-cell depletion, reduced disease activity, and no major toxi ...

A 69-year-old man presented with a history of gradual thickening and wrinkling of the skin on the left side of his face. The physical examination showed hyperkeratosis with accentuated ridging, ...

As a legacy of African enslavement, structural racism affects both population and individual health in three interrelated domains: redlining and racialized residential segregation, mass incarceration ...

Explore this issue of The New England Journal of Medicine (Vol. 390 No. 3).

To the Editor: Vitiligo is a depigmenting skin disorder that can have a substantial effect on patients’ quality of life. In their report on two phase 3 trials of ruxolitinib cream (Topical Ruxolitinib ...

To the Editor: Sanyal et al. (Oct. 21 issue)1 add important new data to our understanding of the natural course of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis (NASH). A substa ...

To the Editor: Morin and Buysse (July 18 issue) 1 provide a comprehensive overview of current assessments and treatments for insomnia. Their emphasis on cognitive behavioral therapy for insomnia as a ...