Two phase 3, randomized trials of inhaled treprostinil for idiopathic pulmonary fibrosis (IPF) were conducted on the basis of preclinical and clinical evidence of an antifibrotic mechanism. TETON-2 ...

In this multicenter trial, we randomly assigned patients 18 to 59 months of age who presented to an emergency department with a moderate-to-severe episode of wheezing to receive azithromycin once ...

Recombinant adeno-associated virus (AAV) vectors are predominantly nonintegrating, but rare genomic integration events have been associated with oncogenesis in neonatal murine models. Here we ...

Avian influenza can jump species from birds to humans, a fact that arouses concern for serious illness and broader human ...

A 50-year-old woman was admitted to the hospital because of vaginal bleeding and anemia. She had a history of fibroids and 1 ...

Clinicians are rightly expected to disclose their gaps in knowledge or their inability to forecast an outcome. Yet emerging AI tools often cannot, or will not, do the same.

In this trial of arthroscopic partial meniscectomy for degenerative medial meniscal tear in adults, participant-reported and radiologic outcomes over 10 years of follow-up suggested no benefit and ...

Explore this issue of The New England Journal of Medicine (Vol. 394 No. 1).

In a study involving 180 blood bags, use of a double-knot closure rather than the usual single knot prevented bacterial ...

Today, the covenant between U.S. academic medical centers and society is under strain: corporatization and the mandate to ...

Explore the current issue of The New England Journal of Medicine (Vol. 394 No. 18).

Explore this issue of The New England Journal of Medicine (Vol. 392 No. 8).