A 91-year-old man with a history of bladder carcinoma and left total knee arthroplasty was evaluated because of left knee pain. A culture of synovial fluid showed no growth. A diagnosis was made.

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 7).

This Sounding Board announces a new FDA policy that the default requirement for FDA approvals will be one robust pivotal trial plus confirmatory evidence, rather than two trials.

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 20).

A 7-year-old boy was brought to a hospital with a 3-month history of cognitive deterioration and seizures. He had contracted measles at 7 months of age while living in an area where the infection is ...

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 15).

To the Editor: The DeLLphi-304 trial reported by Mountzios et al. (July 24 issue)1 represents a landmark step forward for the treatment of relapsed small-cell lung cancer. The delta-like ligand 3 ( ...

Early approaches to restricting abortion access, directed mainly at patients (the demand side of the market), had relatively little impact on national abortion rates. So abortion opponents have turned ...

When a physician’s own incidental finding sends her down a long and winding path to find answers, she finds herself overcome with worry — but also, eventually, a new appreciation for life.

Exercise rehabilitation has a long history in the management of chronic heart failure, with the first randomized trial of exercise training dating back to 1990 1 — and by the late 1990s, it had become ...

Explore this issue of The New England Journal of Medicine (Vol. 390 No. 1).