Environmental factors like maternal smoking and lead exposure interact with genetic vulnerabilities, increasing the risk for ADHD in children.

Moderate alcohol consumption is associated with a substantially elevated risk of premature death, counter to social perceptions.

Substituting sedentary time with physical activity reduces the risk for depression among individuals with obesity and comorbidities.

Psychiatric comorbidities may reduce clinical improvement following interventional pain procedures in adults with chronic pain.

An 8-week cognitive behavioral therapy program targeting inflammatory bowel disease reduces IBD-related disability.

Around 1 in 3 older adults in the US report receiving a drug screening for cannabis or other substances during health care encounters.

Blood lead levels are decreasing among children aged 5 years and younger in the US, though disparities attenuate this trend.

Several people at risk for self-harm share how building social connections and seeking meaning help them mitigate suicide risk.

Limited health literacy is common among primary care patients aged 45 to 64 years, and is associated with poorer health self-management skills.

Objective testing may help assess negative metacognitive bias in veterans with a history of military mild traumatic brain injury.

CSF total tau and p-tau are associated with domain-specific and nonspecific cognitive impairments in patients with ALS.

A new analysis explores the genetic liability of psychiatric disorders using polygenic scores and recurrent copy number variants.