The Trump administration got a chilly reception at the Supreme Court, where a majority of the court questioned President ...

Indianapolis Colts receiver Alec Pierce walked into the locker room Wednesday, took a peek a couple of lockers away and found ...

Indianapolis detectives have arrested a 19-year-old for the July shooting death of a 16-year-old at a gas station on the city ...

The ongoing government shutdown isn’t just the longest in American history. It’s likely the most damaging, too.

Indiana native Benjamin Beeks overcomes Guillain-Barré syndrome to run his first marathon, inspiring others with his story of ...

Police say a tragic mistake led to a deadly shooting in Whitestown, Indiana. Cleaning crew accidentally goes to wrong house, ...

UPS cargo plane crashes in Kentucky after left wing catches fire and engine falls off. At least 9 dead, search for more ...

Many people living with diabetes don’t know their hearts are already under attack. But groundbreaking research hopes to stop ...

The College Football Playoff selection committee has revealed its first rankings, with Ohio State taking the top spot.

Berlin will be the third German city to host a regular-season game when the Indianapolis Colts and Atlanta Falcons square off ...

FBI Indianapolis is joining forces with the Homeland Security Task Force in an initiative to combat violent crime across the ...

Indiana Attorney General secures court judgment against fraudulent timeshare scheme, ending GoGo Travel Consulting's ...