Objective To evaluate the efficacy and safety of early supplementation with insulin glargine (GI) during the acute management of paediatric diabetic ketoacidosis (DKA). Design Double-blinded ...

Attention deficit hyperactivity disorder (ADHD) affects around 1–3% of children. There is a high level of comorbidity with developmental and learning problems as well as with a variety of psychiatric ...

The recent epidemic of childhood obesity[1][1] has raised concern because of the possible clinical and public health consequences.[2,][2][3][3] However, there remains a widespread perception among ...

Background: Difficulty falling asleep (prolonged sleep latency) is a frequently reported problem in school-aged children. Aims: This study aimed to describe the distribution of sleep latency and ...

Objective Impaired fetal and infant growth may cause alterations in developmental programming of the hypothalamic–pituitary–gonadal axis and subsequently pubertal development. We aimed to assess ...

What did you do? We conducted an evaluation of families’ experiences with community and specialist swimming lessons amongst children with disabilities accessing a specialist swimming program. Sparkle ...

Background The use of biologic agents allows the application of precision medicine in the treatment of paediatric severe asthma. Aim To describe the real-life effectiveness of biologic agents in ...

A series of systematic reviews commissioned by the Cass Review and published in Archives of Disease in Childhood.

Since the onset of the COVID-19 pandemic, paediatricians and child mental health practitioners have noticed an increase in tic symptoms in some children and adolescents already diagnosed with tic ...

A 3-week-old infant is diagnosed with tuberous sclerosis complex (TSC) after cardiac rhabdomyomas are detected on prenatal ultrasound and a pathogenic variant in TSC2 is confirmed postnatally through ...

Objectives Describe clinical characteristics, treatment and outcomes of children treated for life-threatening pertussis in paediatric intensive care units during the 2023–2024 outbreak in Great ...

Conclusion Consumption of slush ice drinks containing glycerol may cause a clinical syndrome of glycerol intoxication in young children, characterised by decreased consciousness, hypoglycaemia, lactic ...