Objective To identify factors associated with individual Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI) accrual items in 1385 patients from the ...

Objective Our primary objective was to estimate an updated prevalence of SLE in France in 2020. We also explore the sociodemographic characteristics of patients with SLE, the social and spatial ...

The unpredictable nature of the SLE disease activity makes its management particularly challenging. Current treatment options for SLE focus on managing the inflammatory status, decreasing the symptoms ...

Objective Systemic lupus erythematosus (SLE) disproportionately affects women and often develops during their reproductive years. Research suggests that some women who receive cyclophosphamide as ...

Objective The association of immune-mediated thrombotic thrombocytopenic purpura (iTTP) and SLE was previously described, but patients with iTTP with coexistent SLE remain poorly characterised.

Background The interaction between fine particulate matter (PM2.5) and genetic factors can lead to epigenetic modifications, potentially increasing the risk of SLE development. However, the impact of ...

Objectives To assess brain grey matter alterations in patients with SLE and their correlation with neuropsychological testing using synthetic MRI (SyMRI).Methods This prospective study enrolled ...

Introduction In the type 1 and 2 SLE model, inflammation mediates type 1 manifestations, but its role in type 2 manifestations (eg, fatigue, myalgias, mood disturbance, cognitive dysfunction) is less ...

Objective To report the prevalence of disease activity in individual SLE organ domains, including prevalence stratified by the most common disease activity cut-off score for clinical trial eligibility ...

Objectives To evaluate the Systemic Lupus International Collaborating Clinics-Frailty Index (SLICC-FI) as a predictor of hospitalisations in patients with SLE from a Latin American cohort.Methods ...

Background Mycophenolic acid (MPA) is recommended for the treatment of lupus nephritis (LN). However, the high pharmacokinetic (PK) variability of MPA contributes to its suboptimal efficacy and an ...

Objective This study aims to evaluate the diagnostic performance of the digital liquid chip method (DLCM) compared with indirect immunofluorescence (IIF) and chemiluminescent immunoassay (CLIA) for ...