From overtreating good-risk patients to searching for a cure, Adam Kittai, MD, Perlmutter Cancer Center, outlines where CLL ...
Integrin β6 is expressed in ~90% of NSCLC and correlates with poor prognosis, supporting development of a selective, rapidly internalizing ADC designed to reduce off-target integrin binding.
FDA cleared generic rifapentine for active pulmonary TB (≥12 years) with susceptible isolates, requiring combination therapy with other active antitubercular agents. Authorization also covers LTBI (≥2 ...
Familial pulmonary fibrosis represented 13% of fibrotic ILD overall, with higher proportions in IPF (18%) and unclassifiable ILD (15%) than in SARD-ILD (9%). Across diagnostic subgroups, familial ...
Claims-based ATTR-CM incidence increased >4-fold in Medicare (2010–2021) and ~2.7-fold in commercial insurance (2016–2022), with parallel multi-fold prevalence increases across databases. Higher rates ...
Abnormal creatinine in CKD can justify SGLT2 inhibitor initiation irrespective of diabetes status, given robust renal and ...
Flatiron Telescope uses AI and transparent SQL to turn real-world evidence into quick turnaround oncology research and ...
Current sickle cell disease (SCD) trial eligibility criteria exclude most adults, with only 9.9% meeting inclusion thresholds ...
RBD is characterized by abnormal REM-related behaviors and experiences, often involving threat-themed dream enactment, and requires polysomnographic documentation of REM-associated motor or vocal ...
Patient-authored portal messages surged 153% between 2020 and 2025, far outpacing growth in office visits and effectively creating a largely uncompensated layer of care that health systems and payers ...
Phase 1 BALLI-01 trial results showed promising UCART22 activity in R/R B-cell ALL, with higher remission rates after a ...
Repeatedly assessed resistance training addressed exposure misclassification inherent to single baseline measures, enabling evaluation of long-term patterns across 143,715 participants followed a mean ...
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