INSTALL results showed successful and safe non-viral insertion of large genetic payloads in the livers of mice when delivered by lipid nanoparticles (LNPs). In contrast, mice experienced fatal immune ...

Biopharma needs more engineers with digital manufacturing skills and experience, says Irish training organization, NIBRT.

Researchers based in Austria have developed a new chromatography method for purifying secretory antibody therapies.

Controlling drug-to-antibody ratio and scalable reactors are key to reliable antibody-drug conjugate manufacturing success.

Agentic AI systems fail for the same structural reasons as human organizations, recreating many of the inefficiencies AI aims to eliminate.

Researchers discovered that exposing cancer cells to vibration mimicking vocal cord movement reduced their malignancy.

Lonza and Genetix Biotherapeutics agreed that Lonza will expand capacity to support the manufacture of Genetix’s ZYNTEGLO™, the only FDA-approved gene therapy for pediatric and adult patients with ...

In this GEN Learning Lab, our expert panelists Linda Orzolek, MS, MB, Xuhuai Ji, MD, PhD, and Christina Chang, PhD, will discuss the current landscape of imaging- and next-generation sequencing-based ...

FACE binds to CD71 on the T‑cell surface in CAR T cell preparation, and post-infusion, the same FACE molecules attach to CD71 on leukemia cells.

When the eye’s drainage system clogs, intraocular pressure (IOP) builds up and causes damage. The pressure can lead to glaucoma and vision loss. Researchers headed by a team at Duke University School ...

In intensified bioprocessing, the engineered CHO host supports higher titers and long culture duration in continuous ...

With clinical data beginning to emerge, big pharma is signaling its belief that in vivo CAR generation is the next immunotherapy breakthrough.