The data showed elevated levels of the metabolite αKG improved DNA repair, and blocking it made the cancer cells more sensitive to treatment.

Researchers developed PRINCE, a small-molecule-controlled CRISPR system enabling precise, long-term regulation of gene editing.

The latest update to the ESM protein language model series supports binder design and protein function mapping for therapeutic discovery.

Researchers suggest MutationProjector offers a unifying framework for connecting tumor genotypes to biological mechanisms and therapeutic outcomes.

Eli Lilly has agreed to acquire three privately-held developers of vaccines for infectious diseases for a combined up-to-$3.83 billion cash, in deals intended to expand the acquisitive pharma giant’s ...

The Copenhagen-based team is building an AI platform to target underexplored GPCRs to treat diseases once deemed undruggable.

Parabilis Medicines, the developer of drugs and antibody-drug conjugates targeting historically undruggable protein targets ...

Researchers suggest targeting mTOR activity in aggressive cancers by blocking cholesterol sensing may represent a promising ...

By developing their own functional nerves, these organoids demonstrate how engineering principles can drive biological ...

New AI‑designed miniproteins precisely modulate GPCR signaling and reveal a new screening system for targeting receptors long ...

Roughly 2700 attendees heard a range of perspectives from experts in precision medicine, bioinformatics, and rare disease ...

By mapping how genes relate to one another across biological situations, GSFM creates a reference framework that can help ...