Researchers developed a masked-antibody platform to deliver antibodies into cells. The platform has demonstrated success in ...

Repeated plasma p-tau217 testing showed distinct response patterns during lecanemab treatment, with greater reductions ...

Two studies investigated diverse interactions of metabotropic glutamate receptors. The receptors play an important role in synapse modulation, so the findings reveal insights that could guide ...

MALT1 inhibition shifted immune cells surrounding glioblastomas toward an antitumor state. When combined with temozolomide, MALT1 inhibition enhanced therapeutic efficacy and increased median survival ...

Researchers identified blood protein signatures in children as young as eight that predict future cardiovascular-kidney-metabolic disease risk. Many markers improved with GLP-1 treatment, highlighting ...

Analysis of nearly 59,000 cases found that pneumococcal strains differed in their response to air pollution, with some linked to immediate disease risk and others to delayed risk.

An AI cell model trained on 112 million cells across 12 species has been developed. The tool compares cell types, identifies ...

Researchers tested psilocybin in rodent models, human neurons, and donor nerve tissue. The treatment prevented chemotherapy-induced nerve damage by restoring mitochondrial transport, supporting a ...

Researchers found that m6A marks specific RNAs for transport to distant axons, with YTHDF2, FMRP, and KIF5C helping move the RNA through neurons.

Advanced microscopy and computer simulations revealed how metal ions bridge DNA molecules. The study confirmed a 20-year-old “DNA zipper” model and identified pairing hotspots.

Pterostilbene increased PPARδ signaling by preventing protein degradation, promoting fat breakdown and fatty acid oxidation ...

Researchers delivered amniotic membrane-derived extracellular vesicles via a nasal spray in an Alzheimer’s mouse model. The ...