New research reveals how tiny ‘tunnels’ allow mutant huntingtin protein to spread between neurons, changing our understanding of Huntington’s disease progression and offering a promising therapeutic ...

It’s all well and good designing a novel therapeutic, but these efforts are futile if you’re unable to safely and effectively deliver the treatment at the right time and to the right location. As a ...

A high level of calcium in brain immune cells has been linked to anxiety in healthy mice and in models of chronic anxiety, opening the door to novel anxiety treatments. Researchers had previously ...

Could humans regrow tissue like salamanders or sea stars? This is the question a new study has us asking, as researchers take an early step toward digit regeneration in mice. Introducing a novel ...

Gene expression is controlled, in part, by the interactions between genes and regulatory elements located along the genome. Those interactions depend on the ability of chromatin, a mix of DNA and ...

Since its inception, spatial biology has proven a revolutionary frontier in life science research. However, there is still plenty of room for growth in the systems we use to conduct spatial biology ...

In this infographic, we compare three approaches for collecting spatial data – using imaging-based methods, capture-based sequencing methods and a new class of spatial biology techniques using ...

Complete the form below to discover more on preserving the high molecular sensitivity of single-cell data! While single-cell genomics has greatly advanced our understanding of how cells function in ...

This guide provides a comprehensive overview of the evolution of dPCR, from its humble beginnings to its establishment as a mainstay in the life science lab, before exploring the versatility of this ...

The ability of next-generation sequencing (NGS) technologies to interrogate a broad range of genetic mutations simultaneously has made it a central technique in Cancer research, supporting tumor ...

The modification of lipid nanoparticles with aromatic rings and disulfide bonds enhances mRNA vaccine delivery. Researchers at the University of Pennsylvania (PA, USA) have modified lipid ...

An implantable tissue flap containing muscle and fat alongside a hierarchical network of blood and lymphatic vessels could offer hope for patients with severe tissue damage. An international research ...