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The MEDLINE database was searched for articles from 1966 through to August 2007 using the subject terms 'topical antibiotic ... antibiotic ointment', 'neosporin', 'neomycin', 'bacitracin ...
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and with increasing MRSA infections it is a concern as to how effective these agents will remain. Table 5 summarizes the studies for topical antimicrobials for prevention of infection of wounds.