A clinical trial of a novel over-the-counter gel developed by Peritech Pharma in Yavneh, Israel, proved it effective in treating hemorrhoids and superior to conventional treatment. The randomized, ...

None of which Wyeth, the makers of Preparation H, support. "Applying it to one's chest is an off-label use of Preparation H," said Milicent Brooks, a representative of Wyeth Consumer Healthcare.

Others caution that, while it works, the effects don’t last very long. "It is good to use it only on special occasions. Use a tiny amount of Preparation H cream under the eye area, being careful ...