A 30-year-old woman was evaluated because of back pain, leg stiffness, and falling. Tone was increased in the legs.

A 72-year-old man who had emigrated from Zimbabwe 20 years previously presented with a 17-year history of swelling of the penis, scrotum, and left leg.

The FDA is considering implementing a nicotine product standard, under which cigarettes could contain only very low levels of nicotine. Preparing for the tobacco industry’s potential response is ...

In late March 2024, an adult dairy farm worker had onset of redness and discomfort in the right eye. On presentation that day, subconjunctival hemorrhage and thin, serous drainage were noted in ...

In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information by sharing relevant background and ...

Congenital thrombotic thrombocytopenic purpura (TTP) results from severe hereditary deficiency of ADAMTS13. The efficacy and safety of recombinant ADAMTS13 and standard therapy (plasma-derived ...

Worldwide, cryptococcal meningitis kills up to 180,000 persons annually and is the most common cause of nonviral meningitis in the United States. Besides patients with immunosuppression due to ...

A 63-year-old woman was noted to have white-yellow rings in both eyes. On slit-lamp examination, two concentric rings were seen in each cornea.

In this first episode of a four-part Double Take video miniseries on depression from the New England Journal of Medicine, Dr. Scott-Vernaglia recounts her personal experiences with depression.

To the Editor: In their article on the latest FLAIR platform trial involving patients with chronic lymphocytic leukemia (CLL), Munir and colleagues (Jan. 25 issue) 1 found that the percentage of ...

To the Editor: We welcome Rosenbaum’s commentary on contemporary medical training in her Medicine and Society article (Feb. 8 issue) 1 and do not dispute the veracity of the anecdotal situations ...

Supported by the NIH through grants (U01HL123336 and 1UG3HL164285) to the Clinical Coordinating Center for the trial, grants (U01HL123339 and 1U24HL164284) to the Data Coordinating Center for the ...