Higher risk for cardiovascular mortality, kidney disease progression seen with serum 25(OH)D <10 ng/mL. (HealthDay News) — Vitamin D deficiency is associated with increased risks for cardiovascular ...

“[K]etoconazole-containing regimens are effective and safe for the treatment of castration-resistant prostate cancer,” researchers wrote. Results of a meta-analysis support the use of ketoconazole for ...

Many women with CKD in the US receive suboptimal care that is out of step with guidelines. Contemporary studies continue to document disparities in guideline-based care for women with chronic kidney ...

Benzbromarone demonstrated slightly greater efficacy for the rapid reduction of serum uric acid levels and offered greater anti-inflammatory effects vs febuxostat for the treatment of gout and ...

V1421 carriers have an increased risk for heart failure hospitalization. (HealthDay News) — Male and female V1421 carriers face a similar and substantial risk for heart failure hospitalization, ...

Bicarbonate use vs nonuse by patients with incident CKD is associated with a 1.5-fold higher risk for incident end-stage kidney disease in a fully adjusted model. Oral bicarbonate use by patients ...

US veterans who transition to dialysis are 22% and 43% less likely to be referred to palliative and hospital care, respectively, than those managed conservatively. Patients with advanced chronic ...

A study documents poor outcomes among hospitalized patients with kidney failure and critical limb ischemia who did not receive dialysis. Critical limb ischemia is common among patients with end ...

During a 30-year span from 1990 to 2019, the nationwide incidence of chronic kidney disease increased by 39%. The incidence and prevalence of chronic kidney disease (CKD) has increased ...

Investigators reported an upward trend in the prevalence of polycystic kidney disease, Alport syndrome, lupus nephritis, and focal segmental glomerulosclerosis from 2016 to 2020 and characterized ...

A patient report submitted to the FDA provides insights on living with ARPKD and unmet medical needs. An “ARPKD Therapeutic Development Roadmap” is forthcoming. Current treatments for ...

In a trial, nearly twice as many patients with IgA nephropathy in the iptacopan than placebo group attained a reduction in proteinuria to less than 1 g/g over 9 months. Iptacopan reduces ...