To assess the role of each cysteine residue of v-Src, a series of mutant v-Src in which each one of the cysteine residues was replaced to alanine were constructed by site-directed mutagenesis (Senga ...

A papain-type cysteine endopeptidase with a molecular mass of 35 kDa for the mature enzyme, was purified from germinating castor bean (Ricinus communis L.) endosperm by virtue of its capacity to ...

Pancreatic adenocarcinoma (PAAD) is one of the most lethal malignancies. Although gemcitabine (GEM) is a standard treatment for PAAD, resistance limits its application and therapy. Secoemestrin C (Sec ...

Plant Physiology, Vol. 132, No. 4, Focus Issue: Stress under the Sun: Spotlight on Ultraviolet-B Responses (Aug., 2003), pp. 1892-1900 (9 pages) Sulfhydryl-endopeptidase (SH-EP) is a papain-type ...

Misbehaving proteins are behind many diseases. One way drugmakers incapacitate these bad actors is to deploy molecules that bind to them. But finding solid footholds on the proteins to block their ...

It has previously been reported that cystinuria, as it appears clinically, represents at least three biochemically and genetically distinct diseases. 13 The present studies were undertaken to ...

As the most reactive member of nature’s standard stable of amino acids, cysteine is commonly tapped as a nucleophile in enzyme active sites. But cysteine’s reactivity also makes it uniquely ...

All proteins are built from the same 20 amino acids. One of these, cysteine, was assumed not to have been present at the origin of life. In a new study, scientists have recreated how cysteine was ...

People with high levels of the amino acid cysteine carry 6-10 kilograms more fat than other people. Norwegian researchers studying this phenomenon are generating knowledge which could help to prevent ...

A new study reported in Nature has determined that the amino acid cysteine could promote regeneration among cells in the small intestine. The work showed that cysteine can activate an immune signaling ...