Findings suggest placental mammals that lived in China following the most recent mass extinction evolved large teeth before developing more specialized dental structures associated with different ...

Keratinocytes, which activate an EMT-like program in the skin, can prevent melanoma invasion, highlighting how changes in the tumor microenvironment can act as restraining forces in cancer.

Dissecting protective versus detrimental immune responses uncovers biomarkers and mechanisms that can inform the rational design and evaluation of live attenuated vaccines against African swine fever ...

Metabolic dysfunction-associated steatotic liver disease (MASLD) progression involves the replacement of protective embryo-derived Kupffer cells (KCs) by inflammatory monocyte-derived macrophages ...

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A framework for analyzing single-cell genomics data, in which geometrical properties are harnessed to obtain insights on cellular diversity, including precise clustering, clear visualizations, and ...

Single neurons in mouse sensorimotor cortex are organized by their activity features into distinct subpopulations with area-spanning footprints whose boundaries align closely with anatomical and ...

Interferon receptor knockout chickens uncover how type I and III interferons differentially shape avian antiviral immunity and influenza disease outcomes.

Fine-scale exogenous attention within the foveola selectively enhances contrast gain at low-to-mid spatial frequencies while increasing response gain across a broad spatial frequency range.

The subthalamic nucleus contains subpopulations with different contributions to deliberative decision-making based on noisy evidence and reward-driven preferences.

The viral type 2 internal ribosome entry site uses a unique mechanism to hijack the host ribosomal machinery by interacting with initiator tRNA and 40S head.

Simultaneous tagging of multiple genes with different fluorophores provides a proof of concept for the scalability of tagging all genes in the Caenorhabditis elegans genome.