Some signals help the tumor grow, while others help the immune system fight back. The same signal can thus mean different things in different cells. One example is the JAK-STAT pathway. It helps cells ...

Researchers have developed a new tool that can screen genes involved in human development at unprecedented scale and speed, using it in a proof-of-principle study to reveal new insights into human ...

A new diffusion MRI approach offers a glimpse of the anomalies of cellular architecture underlying basal ganglia degeneration in Huntington’s disease.

Extrachromosomal circular DNA has been identified as a novel component of stress granule cores, indicating its essential involvement in eukaryotic stress response pathways at the level of protein ...

The spatial organization of chromatophore-muscle innervation by motoneurons enables the generation of chromatophore-shaped noise, virtual or composite chromatophores, and shape elements such as lines ...

A study suggests babies’ brains recognize music from as young as three months of age, while spontaneous movements to music emerge by their first birthday and their ability to match movements to it ...

Integrating case counts with genomic sequences quantifies real-time transmission advantages of viral variants.

A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure ...

Although auditory encoding of music is robust early in infancy, the transformation of this input into movement patterns develops substantially over the first postnatal year, without reaching full ...

Computer-Aided Aptamer Modeling and Optimization (CAAMO) enables structure-guided RNA aptamer affinity maturation, producing a SARS-CoV-2 RBD (receptor binding domain) binder that rivals neutralizing ...

Analysis of data across many different studies shows that children's word recognition improves continuously from infancy through age 5 years, and shows strong coupling with early vocabulary.

Celldetective is an open-source software integrating segmentation, tracking, and event detection to perform high-throughput end-to-end study of dynamic cell interactions, without requiring coding ...