This valuable study presents evidence that the human brain encodes perceptual absence and numerical absence through distinct neural codes, while confirming that symbolic and non-symbolic forms of zero ...

This valuable paper reports on a measure of flexible brain state engagement, derived from fMRI, as a predictor of cognitive control. One strength of the study is the use of external datasets for ...

The study presents valuable findings on early behavioral phenotypes that arise in an ADHD-associated adgrl3.1 mutant zebrafish, using a new behavioral approach w ...

This valuable study describes a simple and robust approach for estimating information-limiting noise by splitting neural populations and comparing estimator values. The authors report more accurate ...

This work establishes a valuable theoretical finding about how the spike timing dependence of inhibitory plasticity shapes recurrent network connectivity. The combination of theoretical analysis and ...

This valuable study provides solid evidence that N6 methylation of A74 by METTL3 is required for efficient translation directed by the SARS-CoV-2 5′UTR in unin ...

Strategic pegRNA designs and other approaches mitigating 5' and 3' interactions within pegRNAs can often lead to substantial improvements in prime editing efficiency.

Large scale virtual screening using recently solved structures of Melatonin receptors yield discovery of 10 new high-affinity selective agonists, also revealing novel functional features, including ...

Alongside Research Articles, eLife also publishes scientific discoveries in the form of Tools and Resources papers, Research Advances and Short Reports. eLife is committed to finding new ways of ...

New measures of influenza virus fitness could improve vaccine strain selection through more accurate forecasts of the evolution of the virus.

More than 18 months into the pandemic, the exact death toll of COVID-19 remains elusive. There are several ways to assess how many people have died in a pandemic, each with their advantages and ...

From next year, eLife is eliminating accept/reject decisions after peer review, instead focusing on public reviews and assessments of preprints. Since its inception, eLife’s mission has been to ...