This valuable work extends a previously published regression framework for trial-aligned photometry data incorporating functional variables. However, the evidence is generally incomplete, due to the ...

This important study presents a novel immunotherapy strategy for cancer. The authors develop a whole-tumor cell vaccine comprised of senescent tumor cells and a COX2 inhibitor in a hydrogel matrix.

This study presents a well-executed investigation into how the olfactory system disconnects from the environment during sleep and anesthesia, identifying a potential gating mechanism at the earliest ...

Across multiple analyses controlling for genome-wide relatedness and examining functional immune diversity, the authors find no evidence of HLA/MHC-based (dis)assortative mating, suggesting that ...

Beyond its methodological contribution, the study offers new insights into how stimulus-driven variability and internally generated gain fluctuations evolve over time and between brain areas. The ...

When an article is first published as a Reviewed Preprint in eLife, it includes an eLife Assessment written by the editors and reviewers. This assessment uses a common vocabulary to describe the ...

New funding, awards for metadata and UX excellence, and outstanding research articles are among the highlights of the past year at eLife.