Identification of a nitric oxide-regulated transitional state of Müller glia reveals a key mechanism enabling neuronal regeneration in the injured vertebrate retina.

High-profile news coverage that eLife papers generated in October 2025, including NPR, One Earth and Neuroscience News.

Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

Researchers have mapped the cellular diversity of the eye’s fluid drainage tissue, uncovering a cell subtype that may contribute to glaucoma progression and respond to vitamin B3 treatment.

The authors present convincing data to validate abscisic acid-induced dimerisation to induce a synthetic spindle assembly checkpoint (SAC) arrest that will be of particular importance to analyse ...

The ReproSci project retrospectively analyzed the reproducibility of 1006 claims from 400 papers published between 1959 and 2011 in the field of Drosophila immunity. This project attempts to provide a ...

Proteomics experiments on Drosophila reveal sex-specific effects in aging, and an important role for a protein called DIP-β.

CDK2-mediated TBK1 degradation via Dtx4 represents a previously unrecognized regulatory mechanism that modulates antiviral immunity in fish.

BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

A large-scale investigation of carnivoran brain diversity, providing a unified description of folding patterns, their relationship to behaviour and ecology, and the foundation for future ...

The rise of antibiotic resistance has renewed interest in bacteriophages as therapeutic alternatives. However, co-evolution of phage and bacteria will naturally give rise to phage-resistant pathogens, ...

This valuable study links psychological theories of chunking with a physiological implementation based on short-term synaptic plasticity and synaptic augmentation. The theoretical derivation for ...