Proteomics experiments on Drosophila reveal sex-specific effects in aging, and an important role for a protein called DIP-β.

Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

Identification of a nitric oxide-regulated transitional state of Müller glia reveals a key mechanism enabling neuronal regeneration in the injured vertebrate retina.

Hierarchical communication between cells with distinct positional memories orchestrates the regeneration of missing limb structures in axolotls.

Researchers have mapped the cellular diversity of the eye’s fluid drainage tissue, uncovering a cell subtype that may contribute to glaucoma progression and respond to vitamin B3 treatment.

High-profile news coverage that eLife papers generated in October 2025, including NPR, One Earth and Neuroscience News.

CDK2-mediated TBK1 degradation via Dtx4 represents a previously unrecognized regulatory mechanism that modulates antiviral immunity in fish.